But three weeks after her premature birth, by caesarean section on 22 November, Vanellope, who is named after a Disney princess, has survived three operations at Glenfield Hospital, Leicester, to move her heart back inside her chest.
Vanellope has since undergone two additional surgeries, one to remove the supporting tube and another to place her heart behind the skin of her chest wall.
Vanellope Hope Wilkins is thought to be the first baby born in Britain with a condition called ectopia cordis to survive, according to The Guardian.
She has a rare congenital condition leaving her heart and part of her stomach outside her body.
In a press release, the University Hospitals of Leicester narrated the events surrounding Vanellope Hope, the baby that was born with her heart outside her body. Infection poses a severe risk to babies with this condition.
"At around 50 minutes of age, it was felt that Vanellope was stable enough to be transferred back to the main theatre where she had been born to the waiting anaesthetists, congenital heart disease and pediatric surgical teams who began the task of putting her entire heart back inside her chest", he said.
Vanellope is the first baby to have survived with this condition in the United Kingdom, according to multiple media outlets.
Glenfield Hospital/University Hospitals of Leicester/NHS TrustVanellope was born with her heart located outside her chest.
Vanellope Hope was born prematurely in Leicester on November 22
"I had seen one in fetal life around 20 years ago but that pregnancy was ended", said cardiologist, Frances Bu Lock.
Babies born with this condition have a survival rate of less than 10% due to the risks of infections and other side effects, the hospital added.
Naomi Findlay in a statement on Tuesday said: "I had prepared myself for the worst; that was my way of dealing with it".
Wilkins told the BBC: "She defying everything - it's beyond a miracle". Doctors reported in Circulation that a boy born in the early 2000s had survived for at least three and a half years after surgery.
"I'm now confident she won't wear it so I'm going to donate it to the hospital".
Baby Vanellope is doing well, but her prognosis is uncertain.
Five out of eight per million of babies might face this condition.