One US defense official said that there were "likely fatalities" involved and that rescue teams were on the scene in under an hour.
A U.S. official told ABC news that there was no hostile fire, still they are not ruling it out. There were US personnel on board but it's unclear how many there were on board.
Officials said that rescuers were responding to the location, but other details were not yet available.
An HH-60G Pave Hawk helicopter assigned to the 66th Rescue Squadron flies during training on Nellis Air Force Base, Nevada, Feb. 22, 2018.
A statement from the U.S. Central Command (CENTCOM) confirmed the incident and said that a few U.S. service members were aboard without giving details.
A helicopter of the USA -led worldwide coalition crashed in western Iraq near the border with Syria, the Iraqi military said on Friday.
An investigation will be launched to determine the cause of the crash, CENTCOM says.
Two Americans have lost their lives in Iraq this year in non-combat related incidents.
The Pentagon has acknowledged that it has about 5,200 troops in Iraq that are part of a coalition fighting IS militants.