The other semi-final will feature a Madrid derby, with eleven-time champions Real Madrid taking on neighbours Atletico Madrid.
Vasilyev recognises that Juve are stronger now than they were two years ago, but also warned that Monaco are a different proposition.
Los Blancos and their crosstown rivals have met in two of the past three finals of the competition, but will meet each at the semi-final stage this time around.
Real Madrid, for whom Ronaldo hit a hat-trick as they saw off Bayern Munich in the quarters, are favourites with British bookmakers.
Zinedine Zidane's side could become the first club to retain the trophy in the Champions League era in the final on 3 June in Cardiff.
Their current squad largely consists of somewhat inexperienced but highly talented younger players, most notably the 19-year-old striking sensation Kasper Dolberg, who has bagged 19 goals in all competitions this season.
It can convincingly be argued that this is the more mouthwatering of the two ties - both for its relative novelty value and the contrast and styles and expertise it presents.
"At this level of competition, we knew we were going to play a big team". It's the fourth season in a row we're facing them in Europe and they're a tough opponent.
Can they pull it off?
Juventus players celebrate at the end of the Champions League quarterfinal second leg soccer match between Barcelona and Juventus at Camp Nou stadium in Barcelona, Spain, Wednesday, April 19, 2017.
Nevertheless, the Europa League is a tremendous piece of silverware to win and comes with the added bonus of Champions League qualification.
The second semi, Juventus will take on Monaco.
"This Monaco team have no limits".
Real will host Atletico at the Santiago Bernabeu on May 2 and Monaco are home to Italian champions Juventus on May 3, with the second legs the following week.