If at least two of those teams did not make the College Football Playoff at the end of the season, it would be a major surprise.
Since 2000, Oklahoma has been ranked in the top 10 of the AP Preseason Poll 13 times.
Regardless of who the Tide go up against this season, maintaining the No. 1 ranking throughout the season will be a challenge. Wisconsin was the only team out of these four to win the bowl game.
Coming off a 10-3 season and a victory over MI in the Orange Bowl, Florida State got four first-place votes and was third in the poll - the 16th time since 1988 the Seminoles have started the season in the Top 5.
The ranking matches where the Volunteers started the 2015 season.
"I think systematically, we'll probably use the tight ends a little better", Alabama coach Nick Saban said last week.
Quarterback Jalen Hurts has experience and knows what it takes to succeed.
"They've been a tremendous program for a really long time", Seminoles redshirt sophomore quarterback Deondre Francois said of Alabama.
No. 4 USC is one of four Pac-12 teams in the poll, along with No. 8 Washington, No. 14 Stanford and No. 24 Washington State.
Scarbrough finished third last season in rushing with 812 yards and 11 touchdowns while spending the first part of last season limited by injuries. He has the speed, quickness and strength to become a superstar after missing all of last season due to injury. However, a pass rush featuring Da'Sahawn Hand, Rashaan Evans, Christian Miller and Terrell Hall could be equally imposing. Also, the Crimson Tide will meet the LSU Tigers on November 4 at Bryant-Denny Stadium.
Hours before Florida State and Alabama square off, the Gators will open against No. 11 MI (3:30 p.m., ABC) at AT&T Stadium in Arlington, Texas.
The one bit of bad news for Alabama?
Alabama is a team that is under the constant pressure of high expectations.
When Alabama and FSU football knock heads in just over a week and a half, it will be the fourth time that a team with Saban as an assistant or head coach has faced the Seminoles - and all three times before, he has come up empty handed.