By daybreak, the fire had expanded to about 2,500 acres, and by about 8:30 a.m.it was listed at about 4,000 acres, with hundreds of people under mandatory evacuation orders.
The fire has burned 12,605 acres and was 10 percent contained.
Officials were checking on several reports of people being trapped as a result of the fire, but those have not been confirmed, Los Angeles County Fire Department Supervisor Stafford said.
The LAPD was placed on a citywide tactical alert, which allows commanders to keep officers beyond the end of their shifts, giving them maximum flexibility in deploying resources. Two of the other horses that were rescued were so heated they suffered internal injuries.
The 210 interchange with the Ronald Reagan (118) Freeway was also closed.
The fires have destroyed homes and continue to threaten thousands of homes raising the demand for evacuation for more than a thousand residents.
Evacuations were also issued for Arroyo Street north of the 210 Freeway and areas of Maclay, Pocoima Wash west of Sayre Street and Eldridge, Los Angeles Fire Department spokeswoman Margaret Stewart stated in an update.
A dozen evacuation centers were opened throughout the San Fernando Valley, and all were accepting evacuees, including those with pets. Those centers are the Sylmar Recreation Center and the Sunland Senior Citizen Center.
Numerous animals were being housed at Pierce College and the Los Angeles Equestrian Center, which were at capacity Wednesday afternoon and not accepting additional animals. The fire also forced a mass evacuation of large animals, primarily horses but also others such as alpacas. The fire has come within a quarter-mile from Ventura City Hall.
"Better safe than sorry", Barger said. For small animals, shelters were in place at West Valley Animal Shelter, 20655 Plummer St., and the East Valley Animal Shelter, 14409 Vanowen St.