The two-time Australian Open champion Victoria Azarenka has received a wild card into the tournament, but is doubtful to participate because she has been unwilling to travel without her 1-year-old son, Leo, during a custody dispute with the boy's father.
"Sadly I won't be playing in Melbourne this year, as I am not yet ready to compete", the Scot said in a statement. "Past year we were talking about the health of Rafa Nadal, Roger Federer and Serena Williams and two weeks later they were playing each other in the final".
He is desperate to avoid surgery, saying the chances of a "successful outcome are not as high as I would like".
Confirmation of his absence came hours after Kei Nishikori announced that he, also, wouldn't have enough time to fully recover from a torn wrist tendon before the Australian Open starts January 15 in Melbourne.
"I'm really disappointed for Andy, as I know how much he was looking forward to getting his season started in Brisbane", he said.
Murray flew into Brisbane this week with the intention of playing in his first tournament in over six months, but it was clear in the exhibition set he played in Doha in his stop-over on the way to Australia that there was still a distinct limp in Murray's gait.
Yet, here we are just 18 months later and long-term doubts over Murray's future in tennis have reached fever pitch as a troublesome hip injury that curtailed his hopes of a Wimbledon defence has now led to his latest withdrawal at the Australian Open.
He added that the Murray's decision has to be respected as it is a hard decision for him to take.
Konta played on after receiving treatment but eventually retired
The Aussie, former Wimbledon champion had surgery on both hips during his career and while he never won again at grand slam level, he did return to winning tournaments.
"I think it's very worrying but keeping everything crossed".
The other four men who started 2017 ranked in the top five - Novak Djokovic, Milos Raonic, Stan Wawrinka and Kei Nishikori - were also forced to abbreviate their seasons.
Murray has been a consistent performer at the Australian Open, where he has been a five-time runner-up.
"Everything that I've heard and seen in Abu Dhabi last week - he's nowhere near fit - and I was actually surprised that he actually went down to Brisbane".
"Andy is someone I have always looked up to and he'll be an invaluable mentor for me", said Swan. "I know that when I come back I definitely want to be competing for championships".
"I'm in touch every day with her and with her management team". I thought 9am is pretty good and then he said 8am.