United's performance against Liverpool worked without Pogba because Mourinho employed a low block with two holding midfielders, with the emphasis more on the visitors to attack.
United have won three straight matches since the first-leg draw, with morale-boosting successes against Chelsea and Crystal Palace complemented by Saturday's 2-1 triumph over Liverpool. Add to that the fact that Manchester United are also very impressive at home and this could be a tough game for the visitors.
Antonio Conte's fifth-placed side closed to within two points of Tottenham in the race to qualify for next season's Champions League.
"In these types of games, when the pressure is on you, you just be yourself and I think that's what seems to happen in these games and the team seems to react well, when maybe we don't react as well in other games", said the 20-year-old.
Whether the Special One would go as far as offloading Manchester United's record-signing after two seasons, though, is hard to assess - and it's important to note that Salah and De Bruyne were embroiled in very different situations. "Even in set pieces, corners, unsafe situations - we were in control so I think we deserved it", he said.
Playing wide is improving the game of a player who feels "more comfortable in the middle", but wherever he is deployed the need to "express yourself" is key. An Eric Bailly own goal in the 66th minute saw the visitors claw back but there was no further delight for them as the hosts collected all three points and with it consolidated their grip on second place in the league standings.
A first-half brace from Marcus Rashford proved the difference. "But the reality in this moment is that we have no advantage at all".
The challenge for Mourinho is to pass on his knowledge of how to handle the big occasions, especially the more inexperienced ones in his squad.
Fellow academy graduate Lingard, who had to bide his time at Old Trafford before making an impact, backed his friend to succeed.
"That would let him play the system that worked against Liverpool - and still leave him a formidable defensive platform". He fights for the team, he runs a lot.
There was personal milestone for Petr Cech as he saved a Troy Deeney penalty in a 3-0 win for Arsenal against Watford on way to his Premier League record 200th clean sheet.
"He can make mistakes but Mourinho is not like that and if he has one or two not good games then he puts him out".
It remains to be seen what role, if any, Pogba plays in those fixtures as is going to be short of match sharpness.
"At the end, we could still get a point, but the first half wasn't really good from us".
"We have to defend these situations better".